Soleus fiber force and maximal shortening velocity after non-weight bearing with intermittent activity

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Peak force and maximal shortening velocity of soleus fibers after non-weight-bearing and resistance exercise.

This study examined the effectiveness of resistance exercise as a countermeasure to non-weight-bearing-induced alterations in the absolute peak force, normalized peak force (force/fiber cross-sectional area), peak stiffness, and maximal shortening velocity (Vo) of single permeabilized type I soleus muscle fibers. Adult rats were subjected to the following treatments: normal weight bearing (WB),...

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Effect of intermittent weight bearing on soleus fiber force-velocity-power and force-pCa relationships.

Rat permeabilized type I soleus fibers displayed a 33% reduction in peak power output and a 36% increase in the free Ca2+ concentration required for one-half maximal activation after 14 days of hindlimb non-weight bearing (NWB). We examined the effectiveness of intermittent weight bearing (IWB; consisting of four 10-min periods of weight bearing/day) as a countermeasure to these functional chan...

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Effect of hindlimb unweighting on single soleus fiber maximal shortening velocity and ATPase activity.

This study characterizes the time course of change in single soleus muscle fiber size and function elicited by hindlimb unweighting (HU) and analyzes the extent to which varying durations of HU altered maximal velocity of shortening (Vo), myofibrillar adenosinetriphosphatase (ATPase), and relative content of slow and fast myosin in individual soleus fibers. After 1, 2, or 3 wk of HU, soleus mus...

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Mean Velocity of Fiber Shortening

Previously it was shown that left ventricular (LV) myocardial contractility can be assessed from the instantaneous relation between velocity of fiber shortening and maximum LV wall tension (VcF at max T). Such analysis is complex, requiring frame-by-frame correlation of LV dimensions with pressure, and a simpler approach was sought. In 50 patients the mean velocity of circumferential fiber shor...

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Skeletal muscle fiber atrophy: altered thin filament density changes slow fiber force and shortening velocity.

Single skinned fibers from soleus and adductor longus (AL) muscles of weight-bearing control rats and rats after 14-day hindlimb suspension unloading (HSU) were studied physiologically and ultrastructurally to investigate how slow fibers increase shortening velocity (V0) without fast myosin. We hypothesized that unloading and shortening of soleus during HSU reduces densities of thin filaments, ...

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ژورنال

عنوان ژورنال: Journal of Applied Physiology

سال: 1996

ISSN: 8750-7587,1522-1601

DOI: 10.1152/jappl.1996.80.3.981